I know most everyone uses a mouse as their primary means for doing most everything on a PC and the mice work well. I find that using the mouse and certain keyboard combinations work extremely well for me.

Here are the keyboard combinations I use most frequently:

windows + l - to lock computer
windows + m - minimize all open windows
windows + f - find / search
windows + e - open explorer window
windows + r - open run window
windows + u - open utility manager

control + z - undo
control + x - cut
control + c - copy
control + v - paste
control + n - new window / file
control + a - select all
control + s - save
control + f - find / search
control + p - print
control + o - open file / web page

Hopefully these will be as useful to you as they are to me.

Dave